AELIS FARMA

About the Company

Aelis Farma is a clinical-stage biopharmaceutical company specializing in the development of treatments for brain diseases.
Aelis Farma is developing a new class of drugs: Signaling Specific inhibitors of the CB1 receptor (CB1-SSi) of the endocannabinoid system that provide access to several therapeutic areas without available treatments.
These unique drug candidates, by reproducing a recently discovered natural defense mechanism of the brain , appear to be able to treat various brain pathologies without disrupting normal behavior. A first in pharmacology.
Two initial drug candidates are already in clinical trials in indications with high unmet medical needs:
• AEF0117, to treat disorders due to excessive cannabis use, has already provided evidence of efficacy in a phase 2a clinical study and has entered a phase 2b clinical trial in Q2 2022.
• AEF0217, to treat various cognitive deficits, including those associated with Down syndrome (Trisomy 21), is currently being evaluated in phase 1 clinical trials, with no major adverse effects observed in the three patient cohorts treated to date. Phase 1/2 clinical studies with AEF0217 in Down syndrome subjects are expected to start in Q4 2022. These studies could provide initial efficacy results in H1 2023.
Given the involvement of the CB1 receptor in numerous pathologies, Aelis Farma is also developing using its proprietary platform, several new CB1-SSi with differentiated pharmacological properties to target other brain pathologies.
Based in Bordeaux, within the Inserm Magendie Neurocentre, Aelis Farma has a team of 24 highly qualified employees and has benefited from investments from the Nouvelle-Aquitaine Region, Inserm Transfert Initiative, Bpifrance, regional funds ACI, NACO and Aqui-invest and IRDI Capital Investissement.

Listed Jobs

Company Name

AELIS FARMA

Job Title

Scientific Data Manager

Job Description

Scientific Data Manager
Aelis Farma is looking for a Scientific Data Manager.
The company: Aelis Farma

Aelis Farma’s goal is to develop a new pharmacological class: the signaling specific inhibitors of the CB1 receptor (CB1-SSi). CB1-SSi have a unique mechanism of action that has never been tested in humans before. Aelis Farma currently develops two first-in-class clinical-stage drug candidates: AEF0117 for the treatment of cannabis related disorders, that has just completed a Phase 2B study in the United States in CUD, and AEF0217 for cognitive disorders, including those of Down Syndrome (Trisomy 21), currently in a Phase 1/2 study in Spain in people with Down syndrome. New CB1-SSi compounds are also entering in our pipeline to target other cannabinoid-dependent diseases since Aelis Farma is extremely committed to develop these breakthrough treatments and has the ambition to become the leader in SSi drugs.
Job Functions / Responsibilities:

As part of a dynamic team and in a stimulating environment, you will be responsible for the implementation and customization of the Electronic Lab Notebook (ELN) platform for the Discovery department. You will manage in vitro and in vivo data from the high throughput screening lab and the preclinical team (PoC studies, ADMET). You will lead the development of visualization and analytical tools to improve, advance, and accelerate the discovery and development of new CB1-SSi compounds.

In this context, the tasks to be carried out include:
Participate in the choice of the new ELN platform: collaborate with other team members to identify data analysis and visualization requirements and define the selection criteria
Implement the ELN platform, the corresponding data templates and their associated database models for new or existing workflows
Provide training on system usage and optimizations
Build data management workflows and tools that improve the data collection, storage, analysis and visualization
Define and develop new data analysis and visualization tools
Support lab automatization / digitalization activities and AI implementation
Key Requirements and qualifications:

A PhD degree (mandatory) in Bioinformatics / Computational Biology / Medical Informatics (or equivalent)
Expertise in data management
Experience with ELN platforms (such as Dotmatics, Labguru, etc.)
Experience in database design
Strong programming skills. Some experience using Python to post or retrieve data from APIs and writing SQL queries against relational databases
Familiarity with data science (statistics, machine learning, AI) is preferred
Experience of customized integrations of software and databases
Familiarity with drug discovery processes and pharmacology is preferred but not required
Experience in lab work (biochemical & cell-based assays) would be a plus
Independence and responsibility in decision-making and execution of tasks
Curious, analytical and excited to play with data
Good oral and written communication skills (English and French)

Full-time on-site position to be filled as soon as possible.
We encourage all interested applicants to apply. Please submit the documents in French or English (CV and a cover letter) to m.zanese@aelisfarma.com. Selected candidates will be invited for an interview.

Job Type: Full-time, Permanent, On-site
Status: Cadre
Pay: from 34,000.00€ per year
Work Location: Pessac (Bordeaux area, France)

Bordeaux, France

On site

16-01-2025